VPS39 antibody (C-Term)

Catalog No. ABIN6991489

Product Details anti-VPS39 Antibody

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Binding Specificity: AA 710-760, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS39 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: At least four isoforms of VPS39 are known to exist, this antibody will detect all four. VPS39 antibody is predicted not to cross-react with TRAP1.

Purification: VPS39 Antibody is affinity chromatography purified via peptide column.

Immunogen: VPS39 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human VPS39. The immunogen is located within amino acids 710 - 760 of VPS39.

Isotype: IgG

Application Details

Application Notes: VPS39 antibody can be used for detection of VPS39 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: VPS39 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: VPS39 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for VPS39

Target: VPS39 (Vacuolar Protein Sorting 39 Homolog (VPS39))

Alternative Name: VPS39 (VPS39 Products)

Synonyms: lbk antibody, vam6 antibody, DKFZp469J2314 antibody, A230065P22Rik antibody, AW743070 antibody, Vam6 antibody, Vam6P antibody, mVam6 antibody, TLP antibody, VAM6 antibody, hVam6p antibody, VPS39, HOPS complex subunit antibody, vacuolar protein sorting 39 homolog (S. cerevisiae) antibody, vam6/Vps39-like protein antibody, vacuolar protein sorting 39 antibody, VPS39 HOPS complex subunit antibody, VPS39 antibody, vps39 antibody, LOC100196283 antibody, NAEGRDRAFT_59276 antibody, Vps39 antibody

Background: VPS39 Antibody: VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6.5.

Gene ID: 23339

UniProt: Q96JC1

Pathways: SARS-CoV-2 Protein Interactome