ZNF346 antibody (C-Term)

Catalog No. ABIN6991494

The Rabbit Polyclonal anti-ZNF346 antibody (ABIN6991494) specifically detects ZNF346 in WB, ELISA, IHC (p) and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for ZNF346 antibody (C-Term) (ABIN6991494)

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF346 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-ZNF346 Antibody

Binding Specificity: C-Term

Specificity: ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist, this antibody will recognize the two longest isoforms

Purification: ZNF346 (CT) Antibody is affinity chromatography purified via peptide column.

Immunogen: ZNF346 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human ZNF346. The immunogen is located within the last 50 amino acids of ZNF346.

Isotype: IgG

Application Details

Application Notes: ZNF346 antibody can be used for detection of ZNF346 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZNF346 (CT) Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ZNF346 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZNF346

Target: ZNF346 (Zinc Finger Protein 346 (ZNF346))

Alternative Name: ZNF346

Background: ZNF346 (CT) Antibody: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.

Gene ID: 23567

NCBI Accession: NP_036411

UniProt: Q9UL40