LRRFIP1 antibody (C-Term)

Catalog No. ABIN6991499

The Rabbit Polyclonal anti-LRRFIP1 antibody is suitable to detect LRRFIP1 in samples from Human. It has been validated for WB, ELISA, IF and IHC (p).

Quick Overview for LRRFIP1 antibody (C-Term) (ABIN6991499)

Target: LRRFIP1 (Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRFIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LRRFIP1 Antibody

Binding Specificity: C-Term

Specificity: LRRFIP1 antibody is predicted to not cross-react with other LRRFIP family members. Three isoforms of LRRFIP1 are known to exist, this antibody will only recognize the two longer isoforms.

Purification: LRRFIP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: LRRFIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human LRRFIP1. The immunogen is located within the last 50 amino acids of LRRFIP1.

Isotype: IgG

Application Details

Application Notes: LRRFIP1 antibody can be used for detection of LRRFIP1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRFIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRRFIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LRRFIP1

Target: LRRFIP1 (Leucine Rich Repeat (In FLII) Interacting Protein 1 (LRRFIP1))

Alternative Name: LRRFIP1

Background: LRRFIP1 Antibody: LRRFIP1, also known as GC-binding factor 2 (GCF2), is a 738 amino acid transcriptional repressor that mainly plays a cytoskeletal role. It is primarily localized in the cytoplasm and preferentially binds to GC-rich dsDNA, but will also bind directly to dsRNA as well. The RNA binding domain encompasses a lysine-rich motif. LRRFIP1 interacts with the mammalian Flightless I (Fli-I) and is a key component in the cytoskeletal regulation of platelet function. LRRFIP1 and the related protein LRRFIP2 may modulate canonical WNT signaling and mediate the IRF3-induced production of type I interferon via a beta-catenin-dependent pathway.

Gene ID: 9208

NCBI Accession: NP_001131024

UniProt: Q32MZ4