PAS1C1 antibody (AA 200-250)

Catalog No. ABIN6991569

Product Details anti-PAS1C1 Antibody

Target: PAS1C1 (IFLTD1) (Intermediate Filament Tail Domain Containing 1 (IFLTD1))

Binding Specificity: AA 200-250

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAS1C1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: At least four isoforms of IFLTD1 are known to exist, this antibody will detect all but isoform 4

Purification: IFTLD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: IFLTD1 antibody was raised against an 19 amino acid synthetic peptide near the center of human IFLTD1. The immunogen is located within amino acids 200 - 250 of IFTLD1.

Isotype: IgG

Application Details

Application Notes: IFLTD1 antibody can be used for detection of IFLTD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IFTLD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IFTLD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PAS1C1

Target: PAS1C1 (IFLTD1) (Intermediate Filament Tail Domain Containing 1 (IFLTD1))

Alternative Name: IFTLD1 (IFLTD1 Products)

Synonyms: PAS1C1 antibody, 4933403M22Rik antibody, AI482300 antibody, Lmna-rs1 antibody, Lmna1 antibody, RGD1560077 antibody, lamin tail domain containing 1 antibody, intermediate filament tail domain containing 1 antibody, LMNTD1 antibody, IFLTD1 antibody, Lmntd1 antibody

Background: IFTLD1 Antibody: The intermediate filament tail domain-containing protein (IFLTD1) was initially identified as a candidate gene for pulmonary adenoma susceptibility 1 gene in mice. Transcripts of the gene were only detected in mouse lung tissue from strains carrying the Pas1-susceptible allele. Expression of different alleles of this gene in lung cancer cell lines resulted in different levels of colony formation in in vitro colony formation assays, suggesting that allelic variants of this gene can modulate growth of human cancer cells.

Gene ID: 160492

NCBI Accession: NP_001139200

UniProt: Q8N9Z9