TMEM147 antibody (AA 70-120)
Quick Overview for TMEM147 antibody (AA 70-120) (ABIN6991572)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 70-120
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Purification
- TMEM147 Antibody is affinity chromatography purified via peptide column.
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Immunogen
- TMEM147 antibody was raised against a 13 amino acid synthetic peptide near the center of human TMEM147. The immunogen is located within amino acids 70 - 120 of TMEM147.
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Isotype
- IgG
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Application Notes
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TMEM147 antibody can be used for detection of TMEM147 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- TMEM147 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,4 °C
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Storage Comment
- TMEM147 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TMEM147 (Transmembrane Protein 147 (TMEM147))
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Alternative Name
- TMEM147
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Background
- TMEM147 Antibody: TMEM147 is a recently identified protein that associates with Nicalin and NOMO, forming a complex that is thought to be similar to the gamma-secretase complex. TMEM147 localizes to the endoplasmic reticulum (ER), and in zebrafish, is expressed during early development. TMEM147 also interacts with the M3 muscarinic receptor (M3R) in the ER and is thought to negatively its expression and function.
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Gene ID
- 10430
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NCBI Accession
- NP_116024
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UniProt
- Q9BVK8
Target
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