UHRF1BP1 antibody (AA 890-940)

Catalog No. ABIN6991574

The Rabbit Polyclonal anti-UHRF1BP1 antibody has been validated for ELISA, WB, IF and IHC (p). It is suitable to detect UHRF1BP1 in samples from Human and Mouse.

Quick Overview for UHRF1BP1 antibody (AA 890-940) (ABIN6991574)

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UHRF1BP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-UHRF1BP1 Antibody

Binding Specificity: AA 890-940

Specificity: UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L

Purification: UHRF1BP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1. The immunogen is located within amino acids 890 - 940 of UHRF1BP1.

Isotype: IgG

Application Details

Application Notes: UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: UHRF1BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: UHRF1BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for UHRF1BP1

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Alternative Name: UHRF1BP1

Background: UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

Gene ID: 54887

NCBI Accession: NP_060224

UniProt: Q6BDS2