FXYD7 antibody (N-Term)

Catalog No. ABIN6991576

Product Details anti-FXYD7 Antibody

Target: FXYD7 (FXYD Domain Containing Ion Transport Regulator 7 (FXYD7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FXYD7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: FXYD7 antibody is human, mouse and rat reactive. FXYDY7 antibody is predicted to not react with other members of the FXDY protein family

Purification: FXYD7 Antibody is affinity chromatography purified via peptide column.

Immunogen: FXYD7 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human FXYD7. The immunogen is located within the first 50 amino acids of FXYD7.

Isotype: IgG

Application Details

Application Notes: FXYD7 antibody can be used for detection of FXYD7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FXYD7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FXYD7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FXYD7

Target: FXYD7 (FXYD Domain Containing Ion Transport Regulator 7 (FXYD7))

Alternative Name: FXYD7 (FXYD7 Products)

Synonyms: 1110035I01Rik antibody, FXYD domain containing ion transport regulator 7 antibody, FXYD domain-containing ion transport regulator 7 antibody, FXYD7 antibody, Fxyd7 antibody

Background: FXYD7 Antibody: FXYD7 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing seven invariant and six highly conserved amino acids. The FXYD proteins are tissue-specific regulators of Na, K-ATPase, with FXYD7 initially identified as a brain-specific member. FXYD7 interacts with Na, K-ATPase through its transmembrane domain and is thought to influence the affinity of Na, K-ATPase for external K+ and Na+ ions. Other members of the FXDY family have similar functions: FXYD2 regulates the properties of Na, K-ATPase, while FXYD1 (phospholemman), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.

Gene ID: 53822

UniProt: P58549