RASSF6 antibody (AA 230-280)

Catalog No. ABIN6991597

This Rabbit Polyclonal antibody specifically detects RASSF6 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for RASSF6 antibody (AA 230-280) (ABIN6991597)

Target: RASSF6 (Ras Association Domain-Containing Protein 6 (RASSF6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASSF6 Antibody

Binding Specificity: AA 230-280

Specificity: At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.

Purification: RASSF6 Antibody is affinity chromatography purified via peptide column.

Immunogen: RASSF6 antibody was raised against a 14 amino acid synthetic peptide near the center of human RASSF6. The immunogen is located within amino acids 230 - 280 of RASSF6.

Isotype: IgG

Application Details

Application Notes: RASSF6 antibody can be used for detection of RASSF6 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RASSF6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RASSF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for RASSF6

Target: RASSF6 (Ras Association Domain-Containing Protein 6 (RASSF6))

Alternative Name: RASSF6

Background: RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ,-B pathway and may play a vital role in infection.

Gene ID: 166824

NCBI Accession: NP_803876

UniProt: Q6ZTQ3