ANKLE1 antibody (C-Term)

Catalog No. ABIN6991615

This Chicken Polyclonal antibody specifically detects ANKLE1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ANKLE1 antibody (C-Term) (ABIN6991615)

Target: ANKLE1 (Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))

Reactivity: Human, Rat, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This ANKLE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANKLE1 Antibody

Binding Specificity: C-Term

Specificity: Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2

Purification: ANKLE1 Antibody is affinity chromatography purified via peptide column.

Immunogen: ANKLE1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ANKLE1. The immunogen is located within the last 50 amino acids of ANKLE1.

Isotype: IgY

Application Details

Application Notes: ANKLE1 antibody can be used for detection of ANKLE1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: ANKLE1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: ANKLE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ANKLE1

Target: ANKLE1 (Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))

Alternative Name: ANKLE1

Background: ANKLE1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.

Gene ID: 126549

NCBI Accession: NP_689576

UniProt: Q8NAG6