WDR5 antibody (N-Term)

Catalog No. ABIN6991684

This Rabbit Polyclonal antibody specifically detects WDR5 in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for WDR5 antibody (N-Term) (ABIN6991684)

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-WDR5 Antibody

Binding Specificity: N-Term

Specificity: WDR5 antibody is human specific. WDR5 antibody is predicted to not cross-react with other WDR family members.

Purification: WDR5 Antibody is affinity chromatography purified via peptide column.

Immunogen: WDR5 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human WDR5. The immunogen is located within the first 50 amino acids of WDR5.

Isotype: IgG

Application Details

Application Notes: WDR5 antibody can be used for detection of WDR5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: WDR5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: WDR5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for WDR5

Target: WDR5 (WD Repeat Domain 5 (WDR5))

Alternative Name: WDR5

Background: WDR5 Antibody: WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.

Gene ID: 11091

NCBI Accession: NP_060058

UniProt: P61964