Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CP110 antibody (C-Term)

CCP110 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6991685
  • Target See all CP110 (CCP110) Antibodies
    CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))
    Binding Specificity
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 21
    • 21
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 29
    • 1
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CP110 antibody is un-conjugated
    Application
    • 28
    • 13
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Specificity
    Two isoforms of CCP110 are known to exist, this antibody will only detect the longer isoform
    Purification
    CCP110 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    CCP110 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CCP110. The immunogen is located within the last 50 amino acids of CCP110.
    Isotype
    IgG
    Top Product
    Discover our top product CCP110 Primary Antibody
  • Application Notes
    CCP110 antibody can be used for detection of CCP110 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    CCP110 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    CCP110 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    CP110 (CCP110) (Centriolar Coiled Coil Protein 110kDa (CCP110))
    Alternative Name
    CCP110 (CCP110 Products)
    Synonyms
    6330503K22Rik antibody, AA415922 antibody, AI427129 antibody, AW557948 antibody, CP110 antibody, Cep110 antibody, Cp110 antibody, RGD1310509 antibody, centriolar coiled coil protein 110 antibody, centriolar coiled-coil protein 110 antibody, Ccp110 antibody, CCP110 antibody
    Background
    CCP110 Antibody: CCP110 is a centrosomal protein required for the centrosome to function as a microtubule organizing center and plays an essential role in centrosome duplication. It is a target of cyclin-dependent kinases (CDKs), disruption of CCP110 phosphorylation leads to unscheduled centrosome separation and polyploidy. CCP110 is also a target of SCF (Cyclin F) ubiquitin ligase complex, leading to its degradation, suggesting that this complex controls centrosome homeostasis and mitotic fidelity through CCP110 degradation. The centriolar kinesin Kif24 also interacts with CP110 and remodel microtubules and regulate ciliogenesis.
    Molecular Weight
    Predicted: 110 kDa

    Observed: 110 kDa
    Gene ID
    9738
    NCBI Accession
    NP_001185951
    UniProt
    O43303
    Pathways
    M Phase
You are here:
Support