PHOX2A antibody (C-Term)
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- Target See all PHOX2A Antibodies
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHOX2A antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.
- Purification
- PHOX2A Antibody is affinity chromatography purified via peptide column.
- Immunogen
- PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A. The immunogen is located within the last 50 amino acids of PHOX2A.
- Isotype
- IgG
- Top Product
- Discover our top product PHOX2A Primary Antibody
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- Application Notes
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PHOX2A antibody can be used for detection of PHOX2A by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 2.5 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PHOX2A Antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- PHOX2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- PHOX2A (Paired-Like Homeobox 2a (PHOX2A))
- Alternative Name
- PHOX2A (PHOX2A Products)
- Synonyms
- ARIX antibody, CFEOM2 antibody, FEOM2 antibody, NCAM2 antibody, PMX2A antibody, Arix antibody, Phox2 antibody, Pmx2 antibody, Pmx2a antibody, arix antibody, sou antibody, zgc:77364 antibody, phox2 antibody, xphox2a antibody, paired like homeobox 2a antibody, paired-like homeobox 2a antibody, paired like homeobox 2a S homeolog antibody, PHOX2A antibody, Phox2a antibody, phox2a antibody, phox2a.S antibody
- Background
- PHOX2A Antibody: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.
- Gene ID
- 401
- NCBI Accession
- NP_005160
- UniProt
- O14813
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