TTYH1 antibody (C-Term)

Catalog No. ABIN6991698

Product Details anti-TTYH1 Antibody

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTYH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Specificity: TTYH1 antibody is human specific. Multiple isoforms of TTYH1 are known to exist.

Purification: TTYH1 Antibody is affinity chromatography purified via peptide column.

Immunogen: TTYH1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TTYH1. The immunogen is located within the last 50 amino acids of TTYH1.

Isotype: IgG

Application Details

Application Notes: TTYH1 antibody can be used for detection of TTYH1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TTYH1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TTYH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TTYH1

Target: TTYH1 (Tweety Homolog 1 (TTYH1))

Alternative Name: TTYH1 (TTYH1 Products)

Synonyms: 4930459B04Rik antibody, 6330408P11Rik antibody, tty antibody, TTYH1 antibody, ttyh1-A antibody, tweety family member 1 antibody, tweety family member 1 L homeolog antibody, Protein tweety homolog 1 antibody, Ttyh1 antibody, TTYH1 antibody, ttyh1.L antibody, ttyh-1 antibody

Background: TTYH1 Antibody: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.

Gene ID: 57348

NCBI Accession: NP_001005367

UniProt: Q9H313