VPS13B antibody (N-Term)

Catalog No. ABIN6991715

The Rabbit Polyclonal anti-VPS13B antibody is suitable to detect VPS13B in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IF.

Quick Overview for VPS13B antibody (N-Term) (ABIN6991715)

Target: VPS13B (Vacuolar Protein Sorting 13 Homolog B (Yeast) (VPS13B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS13B antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-VPS13B Antibody

Binding Specificity: AA 90-140, N-Term

Specificity: At least five alternatively spliced transcript variants have been observed. COH1 detects two isoforms.

Purification: COH1 Antibody is affinity chromatography purified via peptide column.

Immunogen: COH1 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human COH1. The immunogen is located within amino acids 90 - 140 of COH1.

Isotype: IgG

Application Details

Application Notes: COH1 antibody can be used for detection of COH1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: COH1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: COH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for VPS13B

Target: VPS13B (Vacuolar Protein Sorting 13 Homolog B (Yeast) (VPS13B))

Alternative Name: COH1

Background: COH1 Antibody: COH1 (Cohen syndrome protein 1), also known as VPS13B (vacuolar protein sorting-associated protein 13B) or CHS1, belongs to the VPS13 family and may function in vesicle-mediated transport and sorting of proteins within the cell. COH1 is widely expressed and multiple alternatively spliced transcript variants have been observed. Mutations in this gene have been associated with Cohen syndrome. COH1 is a Golgi-localized peripheral membrane protein and plays a critical role in Golgi (re)assembly.

Gene ID: 157680

NCBI Accession: NP_056058

UniProt: Q7Z7G8