CCDC22 antibody (N-Term)

Catalog No. ABIN6991716

The Rabbit Polyclonal anti-CCDC22 antibody (ABIN6991716) specifically detects CCDC22 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CCDC22 antibody (N-Term) (ABIN6991716)

Target: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CCDC22 Antibody

Binding Specificity: AA 530-580, N-Term

Specificity: At least three isoforms of CCDC22 are known to exist, this antibody will detect the two largest isoforms.

Purification: CCDC22 Antibody is affinity chromatography purified via peptide column.

Immunogen: CCDC22 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CCDC22. The immunogen is located within amino acids 530 - 580 of CCDC22.

Isotype: IgG

Application Details

Application Notes: CCDC22 antibody can be used for detection of CCDC22 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCDC22 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CCDC22 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CCDC22

Target: CCDC22 (Coiled-Coil Domain Containing 22 (CCDC22))

Alternative Name: CCDC22

Background: CCDC22 Antibody: CCDC22 is a recently identified coiled-coil domain-containing protein that has been shown to bind copines, which are calcium-dependent, membrane-binding proteins that may function in calcium signaling. In rat, CCDC22 has been observed to localize in multiple regions of the brain, including the prefrontal and somatosensory cortex, dentate gyrus and thalamus, and in the ipsilateral motor neurons of the spinal cord after sciatic nerve transection suggesting that it may play a role in neuronal injury response. The human CCDC22 gene has been identified as a novel candidate gene for syndromic X-linked intellectual disability (XLID).

Gene ID: 28952

NCBI Accession: NP_054727

UniProt: O60826