PLAGL2 antibody (N-Term)

Catalog No. ABIN6991761

This anti-PLAGL2 antibody is a Rabbit Polyclonal antibody detecting PLAGL2 in ELISA, WB, IF and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PLAGL2 antibody (N-Term) (ABIN6991761)

Target: PLAGL2 (Pleiomorphic Adenoma Gene-Like 2 (PLAGL2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAGL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PLAGL2 Antibody

Binding Specificity: AA 40-90, N-Term

Specificity: At least two isoforms are known to exist.

Purification: PLAGL2 Antibody is affinity chromatography purified via peptide column.

Immunogen: PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2. The immunogen is located within amino acids 40 - 90 of PLAGL2.

Isotype: IgG

Application Details

Application Notes: PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PLAGL2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PLAGL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PLAGL2

Target: PLAGL2 (Pleiomorphic Adenoma Gene-Like 2 (PLAGL2))

Alternative Name: PLAGL2

Background: PLAGL2 Antibody: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.

Molecular Weight: 55 kDa

Gene ID: 5326

NCBI Accession: NP_002648

UniProt: Q9UPG8