FOXH1 antibody (N-Term)

Catalog No. ABIN6991779

The Rabbit Polyclonal anti-FOXH1 antibody (ABIN6991779) specifically detects FOXH1 in WB, ELISA and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FOXH1 antibody (N-Term) (ABIN6991779)

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-FOXH1 Antibody

Binding Specificity: N-Term

Specificity: FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.

Purification: FOXH1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal FOXH1 antibody was raised against a 19 amino acid peptide near the amino terminus of human FOXH1. The immunogen is located within the first 50 amino acids of FOXH1.

Isotype: IgG

Application Details

Application Notes: FOXH1 antibody can be used for detection of FOXH1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FOXH1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FOXH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FOXH1

Target: FOXH1 (Forkhead Box H1 (FOXH1))

Alternative Name: FOXH1

Background: FOXH1 Antibody: FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.

Molecular Weight: 40 kDa

Gene ID: 8928

NCBI Accession: NP_003914

UniProt: O75593

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling