Formin-Like 1 antibody (C-Term)

Catalog No. ABIN6991782

The Rabbit Polyclonal anti-Formin-Like 1 antibody (ABIN6991782) specifically detects Formin-Like 1 in ELISA, WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Formin-Like 1 antibody (C-Term) (ABIN6991782)

Target: Formin-Like 1 (FMNL1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Formin-Like 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Formin-Like 1 Antibody

Binding Specificity: C-Term

Specificity: FRL1 antibody is human, mouse and rat reactive. Three alternatively spliced transcript variants have been observed

Purification: FRL1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal FRL1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human FRL1. The immunogen is located within the last 50 amino acids of FRL1.

Isotype: IgG

Application Details

Application Notes: FRL1 antibody can be used for detection of FRL1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: FRL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: FRL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Formin-Like 1

Target: Formin-Like 1 (FMNL1)

Alternative Name: FRL1

Background: FRL1 Antibody: The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.

Molecular Weight: 121 kDa

Gene ID: 752

NCBI Accession: NP_005883

UniProt: O95466