RTN4RL2 antibody (C-Term)

Catalog No. ABIN6991792

This Rabbit Polyclonal antibody specifically detects RTN4RL2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for RTN4RL2 antibody (C-Term) (ABIN6991792)

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RTN4RL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RTN4RL2 Antibody

Binding Specificity: AA 330-380, C-Term

Specificity: Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.

Purification: RTN4RL2 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal RTN4RL2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RTN4RL2. The immunogen is located within amino acids 330 - 380 of RTN4RL2.

Isotype: IgG

Application Details

Application Notes: RTN4RL2 antibody can be used for detection of RTN4RL2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RTN4RL2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: RTN4RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for RTN4RL2

Target: RTN4RL2 (Reticulon 4 Receptor-Like 2 (RTN4RL2))

Alternative Name: RTN4RL2

Background: RTN4RL2 Antibody: Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Molecular Weight: Predicted: 46 kDa

Gene ID: 349667

NCBI Accession: NP_848665

UniProt: Q86UN3