GRINA antibody (AA 110-160)
Quick Overview for GRINA antibody (AA 110-160) (ABIN6991793)
Target
See all GRINA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 110-160
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Specificity
- GRINA antibody is predicted to not cross-react with other members of the TMBIM family.
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Purification
- GRINA Antibody is affinity chromatography purified via peptide column.
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Immunogen
- Rabbit polyclonal GRINA antibody was raised against an 18 amino acid peptide near the center of human GRINA. The immunogen is located within amino acids 110 - 160 of GRINA.
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Isotype
- IgG
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Application Notes
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GRINA antibody can be used for detection of GRINA by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- GRINA Antibody is supplied in PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,4 °C
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Storage Comment
- GRINA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GRINA (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Associated Protein 1 (Glutamate Binding) (GRINA))
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Alternative Name
- GRINA
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Background
- GRINA Antibody: The transmembrane BAX inhibitor motif (TMBIM) family of proteins includes the founder member TMBIM6/BI-1, TMBIM1/RECS1 (responsive to centrifugal force and shear stress gene 1 protein), TMBIM2/LFG (life guard), TMBIM3/GRINA (glutamate receptor ionotropic NMDA protein 1), TMBIM4/GAAP (Golgi anti-apoptotic-associated protein), and TMBIM5/GHTIM (growth hormone-inducible transmembrane protein). They are highly conserved in mammals and zebrafish and contain a conserved BAX inhibitor-1 motif. GRINA is expressed in the brain and is a potential apoptotic regulator.
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Molecular Weight
- Predicted: 41 kDa
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Gene ID
- 2907
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NCBI Accession
- NP_001009184
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UniProt
- Q7Z429
Target
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