DHX36 antibody (C-Term)

Catalog No. ABIN6991798

This Rabbit Polyclonal antibody specifically detects DHX36 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for DHX36 antibody (C-Term) (ABIN6991798)

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX36 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DHX36 Antibody

Binding Specificity: C-Term

Specificity: At least four isoforms of DDX36 are known to exist, this antibody will detect the three longest isoforms.

Purification: DHX36 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal DHX36 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DHX36. The immunogen is located within the last 50 amino acids of DHX36.

Isotype: IgG

Application Details

Application Notes: DHX36 antibody can be used for detection of DHX36 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: DHX36 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: DHX36 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for DHX36

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Alternative Name: DHX36

Background: DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.

Molecular Weight: Predicted: 111 kDa

Gene ID: 170506

NCBI Accession: NP_065916

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades