TSC22D3 antibody (N-Term)

Catalog No. ABIN6991815

The Rabbit Polyclonal anti-TSC22D3 antibody (ABIN6991815) specifically detects TSC22D3 in WB, ELISA, IF and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for TSC22D3 antibody (N-Term) (ABIN6991815)

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC22D3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-TSC22D3 Antibody

Binding Specificity: AA 40-90, N-Term

Purification: TSC22D3 Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3. The immunogen is located within amino acids 40 - 90 of TSC22D3.

Isotype: IgG

Application Details

Application Notes: TSC22D3 antibody can be used for detection of TSC22D3 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TSC22D3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TSC22D3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Alternative Name: TSC22D3

Background: TSC22D3 Antibody: The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-κ,B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-κ,B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.

Molecular Weight: Predicted: 22 kDa

Observed: 23 kDa

Gene ID: 1831

NCBI Accession: NP_932174

UniProt: Q99576