PRKCDBP antibody (AA 150-200)

Catalog No. ABIN6991835

Product Details anti-PRKCDBP Antibody

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Binding Specificity: AA 150-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKCDBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: It is predicted to not cross-react with other members of the cavin family.

Purification: PRKCDBP Antibody is affinity chromatography purified via peptide column.

Immunogen: Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP. The immunogen is located within amino acids 150 - 200 of PRKCDBP.

Isotype: IgG

Application Details

Application Notes: PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRKCDBP Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PRKCDBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PRKCDBP

Target: PRKCDBP (Protein Kinase C, delta Binding Protein (PRKCDBP))

Alternative Name: PRKCDBP (PRKCDBP Products)

Synonyms: PRKCDBP antibody, CAVIN3 antibody, HSRBC antibody, SRBC antibody, cavin-3 antibody, 3110015B12Rik antibody, 6330514M23Rik antibody, DIG-2 antibody, Srbc antibody, caveolae associated protein 3 antibody, caveolae associated 3 antibody, CAVIN3 antibody, Cavin3 antibody

Background: PRKCDBP Antibody: The protein kinase C delta (PKC-δ,) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ, but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.

Molecular Weight: 29 kDa

Gene ID: 112464

NCBI Accession: NP_659477

UniProt: Q969G5