PRRT2 antibody (AA 180-230)

Catalog No. ABIN6991846

This Rabbit Polyclonal antibody specifically detects PRRT2 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PRRT2 antibody (AA 180-230) (ABIN6991846)

Target: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRRT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PRRT2 Antibody

Binding Specificity: AA 180-230

Specificity: Multiple isoforms of PRRT2 are known to exist.

Purification: PRRT2 Antibody is affinity chromatography purified via peptide column.

Immunogen: PRRT2 antibody was raised against a 18 amino acid peptide near the center of human PRRT2 . The immunogen is located within amino acids 180 - 230 of PRRT2.

Isotype: IgG

Application Details

Application Notes: PRRT2 Antibody can be used for detection of PRRT2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRRT2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PRRT2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PRRT2

Target: PRRT2 (Proline-Rich Transmembrane Protein 2 (PRRT2))

Alternative Name: PRRT2

Background: PRRT2 Antibody: The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord in embryonic and postnatal stages. While little is known of the function of this protein, mutations in PRRT2 have been shown to be the causative gene of paroxysmal kinesigenic dyskinesia, which is characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements. Recent studies have shown that PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

Molecular Weight: Predicted: 43 kDa

Observed: 44 kDa

Gene ID: 112476

NCBI Accession: NP_001243371

UniProt: Q7Z6L0