TRIM24 antibody (AA 530-580)

Catalog No. ABIN6991871

The Rabbit Polyclonal anti-TRIM24 antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect TRIM24 in samples from Human, Mouse and Rat.

Quick Overview for TRIM24 antibody (AA 530-580) (ABIN6991871)

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM24 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-TRIM24 Antibody

Binding Specificity: AA 530-580

Specificity: At least two isoforms of TRIM24 are known to exist.

Purification: TRIM24 Antibody is affinity chromatography purified via peptide column.

Immunogen: TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.

Isotype: IgG

Application Details

Application Notes: TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TRIM24

Target: TRIM24 (Tripartite Motif Containing 24 (TRIM24))

Alternative Name: TRIM24

Background: TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).

Molecular Weight: Predicted: 112, 116

Observed: 108, 1 of 2 isoforms kDa

Gene ID: 8805

NCBI Accession: NP_056989

UniProt: O15164