CD160 antibody (AA 50-100)

Catalog No. ABIN6991903

This Rabbit Polyclonal antibody specifically detects CD160 in WB, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD160 antibody (AA 50-100) (ABIN6991903)

Target: CD160

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD160 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-CD160 Antibody

Binding Specificity: AA 50-100

Specificity: CD160 antibody is human and mouse reactive. Multiple isoforms of CD160 are known to exist.

Purification: CD160 Antibody is affinity chromatography purified via peptide column.

Immunogen: CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160. The immunogen is located within amino acids 50 - 100 of CD160 .

Isotype: IgG

Application Details

Application Notes: CD160 antibody can be used for detection of CD160 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: CD160 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: CD160 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for CD160

Target: CD160

Alternative Name: CD160

Background: CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).

Molecular Weight: Predicted: 20 kDa

Observed: 25kDa

Gene ID: 11126

NCBI Accession: NP_008984

UniProt: O95971