IL28B antibody (AA 120-170)

Catalog No. ABIN6991905

Product Details anti-IL28B Antibody

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Binding Specificity: AA 120-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL28B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificity: IL-28B antibody is human specific. IL-28B antibody may cross-react with IL-28A and IL-29.

Purification: IL-28B Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-28B antibody was raised against a 17 amino acid peptide near the center of human IL-28B. The immunogen is located within amino acids 120 - 170 of IL-28B .

Isotype: IgG

Application Details

Application Notes: IL-28B antibody can be used for detection of IL-28B by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-28B Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IL-28B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL28B

Target: IL28B (Interleukin 28B (Interferon, lambda 3) (IL28B))

Alternative Name: IL-28B (IL28B Products)

Synonyms: Il28b antibody, IFL-1 antibody, IL-28B antibody, INF-alpha antibody, INF-lambda antibody, Il28 antibody, IL28B antibody, IL28C antibody, interferon, lambda 3 antibody, interferon lambda 3 antibody, Ifnl3 antibody, IFNL3 antibody

Background: Interleukin 28 (IL-28B), also known as interferon lambda 3, is cytokine distantly related to type I interferons and the IL-10 family (1). The IL-28B gene and the closely related cytokine genes IL-28A and IL-29 form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection and can induce anti-viral activity (2,3). All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor-beta (IL10RB) and interleukin 28 receptor- alpha (IL28RA) (1).

Molecular Weight: Predicted: 20 kDa

Observed: 16kDa

Gene ID: 282617

NCBI Accession: NP_742151

UniProt: Q8IZI9