LRRC26 antibody (C-Term)

Catalog No. ABIN6991925

The Rabbit Polyclonal anti-LRRC26 antibody is suitable to detect LRRC26 in samples from Human. It has been validated for WB, ELISA, IHC (p) and IF.

Quick Overview for LRRC26 antibody (C-Term) (ABIN6991925)

Target: LRRC26 (Leucine Rich Repeat Containing 26 (LRRC26))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC26 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-LRRC26 Antibody

Binding Specificity: C-Term

Specificity: LRRC26 antibody is human specific.

Purification: LRRC26 antibody is affinity chromatography purified via peptide column.

Immunogen: LRRC26 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LRRC26. The immunogen is located within the last 50 amino acids of LRRC26.

Isotype: IgG

Application Details

Application Notes: LRRC26 antibody can be used for detection of LRRC26 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRC26 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: LRRC26 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for LRRC26

Target: LRRC26 (Leucine Rich Repeat Containing 26 (LRRC26))

Alternative Name: LRRC26

Background: The LRRC26 protein was initially identified as a cytokeratin-associated protein whose expression was elevated in multiple cancer cell lines and cancer specimens as well in normal prostate and salivary gland tissues (1). LRRC26 was later found to negatively regulate the NF-kappaB activation and suppresses tumor growth and metastasis (2). LRRC26 can also act to selectively alter the efficacy of large conductance calcium-activated K (BK) channels (3).

Molecular Weight: Predicted: 37 kDa

Observed: 48 kDa

Gene ID: 389816

NCBI Accession: NP_001013675

UniProt: Q2I0M4