TMIGD1 antibody (AA 150-200)

Catalog No. ABIN6991945

This Rabbit Polyclonal antibody specifically detects TMIGD1 in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TMIGD1 antibody (AA 150-200) (ABIN6991945)

Target: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMIGD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-TMIGD1 Antibody

Binding Specificity: AA 150-200

Specificity: TMIGD1 antibody is human, mouse and rat reactive. At least two isoforms of TMIGD1 are known to exist, this antibody will detect both isoforms.

Purification: TMIGD1 antibody is affinity chromatography purified via peptide column.

Immunogen: TMIGD1 antibody was raised against an 18 amino acid peptide near the center of human TMIGD1. The immunogen is located within amino acids 150 - 200 of TMIGD1.

Isotype: IgG

Application Details

Application Notes: TMIGD1 antibody can be used for detection of TMIGD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMIGD1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: TMIGD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for TMIGD1

Target: TMIGD1 (Transmembrane and Immunoglobulin Domain Containing 1 (TMIGD1))

Alternative Name: TMIGD1

Background: TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2). It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane (1). TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium (2-4). TMIGD1 has also been postulated to play a role in cell adhesion (2).

Molecular Weight: Predicted: 29 kDa

Observed: 24 kDa

Gene ID: 388364

NCBI Accession: NP_996663

UniProt: Q6UXZ0