GLIPR1L1 antibody (N-Term)
Quick Overview for GLIPR1L1 antibody (N-Term) (ABIN6991950)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-70, N-Term
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Specificity
- GLIPR1L1 antibody is human specific. At least two isoforms of GLIPR1L1 are known to exist, this antibody will detect both isoforms. This antibody is predicted to not cross-react with other GLIPR or GLIPR-like proteins.
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Purification
- GLIPR1L1 antibody is affinity chromatography purified via peptide column.
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Immunogen
- GLIPR1L1 antibody was raised against an 18 amino acid peptide near the amino terminus of human GLIPR1L1 . The immunogen is located within amino acids 20 - 70 of GLIPR1L1.
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Isotype
- IgG
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Application Notes
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GLIPR1L1 antibody can be used for detection of GLIPR1L1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- GLIPR1L1 antibody is supplied in PBS containing 0.02 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C,4 °C
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Storage Comment
- GLIPR1L1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- GLIPR1L1 (GLI Pathogenesis-Related 1 Like 1 (GLIPR1L1))
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Alternative Name
- GLIPR1L1
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Background
- The GLIPR1-like 1 protein (GLIPR1L1) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2 (1). GLIPR1L1 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family (2). GLIPR1 is a tumor suppressor whose expression is regulated by p53 (3). Unlike GLIPR1, GLIPR1L1 is expressed primarily in the testis and is thought to be involved in the binding of sperm to the oocyte complex (4).
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Molecular Weight
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Predicted: 26 kDa
Observed: 23 kDa -
Gene ID
- 256710
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NCBI Accession
- NP_689992
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UniProt
- Q6UWM5
Target
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