WDR61 antibody (N-Term)

Catalog No. ABIN6992069

Product Details anti-WDR61 Antibody

Target: WDR61 (WD Repeat Domain 61 (WDR61))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR61 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: WDR61 antibody is human, mouse and rat reactive.

Purification: WDR61 antibody is affinity chromatography purified via peptide column.

Immunogen: WDR61 antibody was raised against a 14 amino acid peptide near the amino terminus of human WDR61. The immunogen is located within the first 50 amino acids of WDR61.

Isotype: IgG

Application Details

Application Notes: WDR61 antibody can be used for detection of WDR61 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: WDR61 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: WDR61 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for WDR61

Target: WDR61 (WD Repeat Domain 61 (WDR61))

Alternative Name: WDR61 (WDR61 Products)

Synonyms: WDR61 antibody, REC14 antibody, SKI8 antibody, 2700038L12Rik antibody, 2810418I05Rik antibody, RGD1308228 antibody, WD repeat domain 61 antibody, Ski complex subunit Rec14 antibody, WD repeat domain 61 L homeolog antibody, wdr61 antibody, WDR61 antibody, LOC692852 antibody, LOC732907 antibody, rec14 antibody, Wdr61 antibody, wdr61.L antibody

Background: WDR61 (WD-repeat-containing protein 61), also known as SKI8 or REC14, is a subunit of the human PAF and SKI complexes, which function in transcriptional regulation and are involved in events downstream of RNA synthesis, such as RNA surveillance (1,2). PAF1C is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1C (3,4).

Molecular Weight: Predicted: 34 kDa

Observed: 30 kDa

Gene ID: 80349

NCBI Accession: NP_079510

UniProt: Q9GZS3