SKIV2L antibody (N-Term)

Catalog No. ABIN6992073

The Rabbit Polyclonal anti-SKIV2L antibody (ABIN6992073) specifically detects SKIV2L in ELISA, WB, IF and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SKIV2L antibody (N-Term) (ABIN6992073)

Target: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SKIV2L antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SKIV2L Antibody

Binding Specificity: AA 60-110, N-Term

Specificity: SKI2W antibody is human, mouse and rat reactive. At least two isoforms of SKI2W are known to exist, this antibody will detect both isoforms.

Purification: SKI2W antibody is affinity chromatography purified via peptide column.

Immunogen: SKI2W antibody was raised against a 16 amino acid peptide near the amino terminus of human SKI2W. The immunogen is located within amino acids 60 - 110 of SKI2W.

Isotype: IgG

Application Details

Application Notes: SKI2W antibody can be used for detection of SKI2W by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SKI2W antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SKI2W antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SKIV2L

Target: SKIV2L (Superkiller Viralicidic Activity 2-Like (SKIV2L))

Alternative Name: SKI2W

Background: SKI2W (SKIV2L, Helicase-like protein), a DEVH-box protein, is a component of the SKI complex which is involved in the regulation of translation and RNA turnover (1,2). SKI2W is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain (2). The potential roles of Ski2W on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus (3,4).

Molecular Weight: Predicted: 113, 137 kDa

Observed: 135 kDa

Gene ID: 6499

NCBI Accession: NP_008860

UniProt: Q15477