KCNK1 antibody (C-Term)

Catalog No. ABIN6992080

This Rabbit Polyclonal antibody specifically detects KCNK1 in ELISA, WB, IHC (p) and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for KCNK1 antibody (C-Term) (ABIN6992080)

Target: KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-KCNK1 Antibody

Binding Specificity: AA 220-270, C-Term

Specificity: KCNK1 antibody is human, mouse and rat reactive. KCNK1 antibody is predicted to not cross-react with other KCNK proteins.

Purification: KCNK1 antibody is affinity chromatography purified via peptide column.

Immunogen: KCNK1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human KCNK1. The immunogen is located within amino acids 220 - 270 of KCNK1.

Isotype: IgG

Application Details

Application Notes: KCNK1 antibody can be used for detection of KCNK1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KCNK1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: KCNK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for KCNK1

Target: KCNK1 (Potassium Channel Subfamily K Member 1 (KCNK1))

Alternative Name: KCNK1

Background: The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).

Molecular Weight: Predicted: 37 kDa

Observed: 35 kDa

Gene ID: 3775

NCBI Accession: NP_002236

UniProt: O00180