PRRX1 antibody (AA 70-120)

Catalog No. ABIN6992105

Product Details anti-PRRX1 Antibody

Target: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Binding Specificity: AA 70-120

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRRX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: PRRX1 antibody is human, mouse and rat reactive. At least two isoforms of PRRX1 are known to exist, this antibody will detect both isoforms.

Purification: PRRX1 antibody is affinity chromatography purified via peptide column.

Immunogen: PRRX1 antibody was raised against a 19 amino acid peptide near the center of human PRRX1. The immunogen is located within amino acids 70 - 120 of PRRX1.

Isotype: IgG

Application Details

Application Notes: PRRX1 antibody can be used for detection of PRRX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PRRX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: PRRX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for PRRX1

Target: PRRX1 (Paired Related Homeobox 1 (PRRX1))

Alternative Name: PRRX1 (PRRX1 Products)

Synonyms: AGOTC antibody, PHOX1 antibody, PMX1 antibody, PRX-1 antibody, PRX1 antibody, A230024N07Rik antibody, AA755424 antibody, AI385634 antibody, AI843499 antibody, K-2 antibody, Pmx antibody, Pmx1 antibody, Prx1 antibody, mHox antibody, Prx-1 antibody, gMHox antibody, homeobox antibody, pmx1 antibody, cb329 antibody, prrx1 antibody, zgc:64055 antibody, wu:fa09h05 antibody, wu:fb52c01 antibody, PRRX1 antibody, fa97b09 antibody, wu:fa97b09 antibody, zgc:101095 antibody, zgc:64199 antibody, paired related homeobox 1 antibody, paired related homeobox 1a antibody, paired related homeobox 1b antibody, PRRX1 antibody, Prrx1 antibody, prrx1a antibody, prrx1b antibody

Background: The paired related homeobox protein 1 (PRRX1) is a paired-type DNA-binding homeodomain that plays an important role as a key switch for neural cell lineage determination and is essential for development (1,2). PRRX1 is expressed in a number of undifferentiated mesenchymal cells in mouse embryos and adults (3). Mice with a disrupted PRRX1 gene show perinatal death with craniofacial and limb malformations (4). Low PRRX1 expression levels were significantly associated with metastasis and poor prognosis of breast and colorectal cancer (5).

Molecular Weight: Predicted: 27 kDa

Observed: 26 kDa

Gene ID: 5396

NCBI Accession: NP_073207

UniProt: P54821