IKZF2 antibody (N-Term)

Catalog No. ABIN6992112

Product Details anti-IKZF2 Antibody

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Binding Specificity: AA 50-100, N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: IKZF2 antibody is human, mouse and rat reactive. At least two isoforms of IKZF2 are known to exist, this antibody will detect both isoforms. IKZF2 antibody is predicted to not cross-react with other IKZF proteins.

Purification: IKZF2 antibody is affinity chromatography purified via peptide column.

Immunogen: IKZF2 antibody was raised against a 19 amino acid peptide near the amino terminus of human IKZF2. The immunogen is located within amino acids 50 - 100 of IKZF2.

Isotype: IgG

Application Details

Application Notes: IKZF2 antibody can be used for detection of IKZF2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IKZF2 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: IKZF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Alternative Name: IKZF2 (IKZF2 Products)

Synonyms: ANF1A2 antibody, HELIOS antibody, ZNF1A2 antibody, ZNFN1A2 antibody, helios antibody, znf1a2 antibody, znfn1a1 antibody, znfn1a2 antibody, IKZF2 antibody, MGC159581 antibody, DKFZp469N0319 antibody, A730095J18Rik antibody, Helios antibody, Zfpn1a2 antibody, Znfn1a2 antibody, ikzf2 antibody, znfn1a1-a antibody, IKAROS family zinc finger 2 antibody, si:zfos-1425h8.1 antibody, IKAROS family zinc finger 2 (Helios) antibody, IKAROS family zinc finger 2 L homeolog antibody, IKZF2 antibody, ikzf2 antibody, Ikzf2 antibody, si:zfos-1425h8.1 antibody, ikzf2.L antibody

Background: The Ikaros family zinc finger 2 (IKZF2) is a member of the Ikaros family of zinc-finger proteins, a family of hematopoietic-specific transcription factors involved in the regulation of lymphocyte development (1,2). IKZF2 forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development (3). Its expression is a marker for T cell activation and proliferation (4).

Molecular Weight: Predicted: 58 kDa

Observed: 60 kDa

Gene ID: 22807

NCBI Accession: NP_057344

UniProt: Q9UKS7