SOX4 antibody (N-Term)

Catalog No. ABIN6992114

The Rabbit Polyclonal anti-SOX4 antibody has been validated for WB, ELISA, IHC (p) and IF. It is suitable to detect SOX4 in samples from Human, Mouse and Rat.

Quick Overview for SOX4 antibody (N-Term) (ABIN6992114)

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-SOX4 Antibody

Binding Specificity: N-Term

Specificity: SOX4 antibody is human, mouse and rat reactive.

Purification: SOX4 antibody is affinity chromatography purified via peptide column.

Immunogen: SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4. The immunogen is located within the first 50 amino acids of SOX4.

Isotype: IgG

Application Details

Application Notes: SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: SOX4 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: SOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4

Background: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).

Molecular Weight: Predicted: 52 kDa

Observed: 520 kDa

Gene ID: 6659

NCBI Accession: NP_003098

UniProt: Q06945