SOX4 antibody (N-Term)
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- Target See all SOX4 Antibodies
- SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOX4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Specificity
- SOX4 antibody is human, mouse and rat reactive.
- Purification
- SOX4 antibody is affinity chromatography purified via peptide column.
- Immunogen
- SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4. The immunogen is located within the first 50 amino acids of SOX4.
- Isotype
- IgG
- Top Product
- Discover our top product SOX4 Primary Antibody
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- Application Notes
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SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- SOX4 antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- SOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))
- Alternative Name
- SOX4 (SOX4 Products)
- Synonyms
- EVI16 antibody, AA682046 antibody, Sox-4 antibody, sox4 antibody, wu:fb82f08 antibody, wu:fq41g10 antibody, zgc:65850 antibody, zgc:77392 antibody, SRY-box 4 antibody, SRY box 4 antibody, SRY (sex determining region Y)-box 4 antibody, SRY (sex determining region Y)-box 4a antibody, SOX4 antibody, Sox4 antibody, sox4a antibody
- Background
- SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).
- Molecular Weight
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Predicted: 52 kDa
Observed: 520 kDa - Gene ID
- 6659
- NCBI Accession
- NP_003098
- UniProt
- Q06945
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