HOPX antibody (N-Term)

Catalog No. ABIN6992122

This Rabbit Polyclonal antibody specifically detects HOPX in WB, ELISA, IHC (p) and IF. It exhibits reactivity toward Human.

Quick Overview for HOPX antibody (N-Term) (ABIN6992122)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-HOPX Antibody

Binding Specificity: N-Term

Specificity: HOPX antibody is human specific. At least three isoforms of HOPX are known to exist, this antibody will detect all three isoforms.

Purification: HOPX antibody is affinity chromatography purified via peptide column.

Immunogen: HOPX antibody was raised against a 16 amino acid peptide near the amino terminus of human HOPX. The immunogen is located within the first 50 amino acids of HOPX.

Isotype: IgG

Application Details

Application Notes: HOPX antibody can be used for detection of HOPX by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: HOPX antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: HOPX antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX

Background: HOPX is a small homeodomain protein that lacks normally conserved residues required for DNA binding (1). It is thought to act downstream of NKX2-5 and modulates serum response factor (SRF)-dependent cardiac-specific gene expression and cardiac development (1). HOPX also acts a tumor suppressor gene in multiple tumors and cancer cell lines (2,3). HOPX has been reported to regulate the proliferation/differentiation homeostasis in different cell types, including keratinocytes (4).

Molecular Weight: Predicted: 12 kDa

Observed: 18 kDa

Gene ID: 84525

NCBI Accession: NP_001138932

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation