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KIR2DS2 antibody (C-Term)

KIR2DS2 Reactivity: Human WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6992145
  • Target See all KIR2DS2 Antibodies
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    Binding Specificity
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human
    Host
    • 26
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    This KIR2DS2 antibody is un-conjugated
    Application
    • 21
    • 16
    • 16
    • 10
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
    Purification
    KIR2DS2 antibody is affinity chromatography purified via peptide column.
    Immunogen
    KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2. The immunogen is located within the last 50 amino acids of KIR2DS2.
    Isotype
    IgG
    Top Product
    Discover our top product KIR2DS2 Primary Antibody
  • Application Notes
    KIR2DS2 antibody can be used for detection of KIR2DS2 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    KIR2DS2 antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,4 °C
    Storage Comment
    KIR2DS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
    Alternative Name
    KIR2DS2 (KIR2DS2 Products)
    Synonyms
    183ActI antibody, CD158J antibody, CD158b antibody, NKAT5 antibody, cl-49 antibody, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antibody, KIR2DS2 antibody
    Background
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells (1). The KIR proteins are classified by the number of extracellular immunoglobulin domains and by whether they have a long (L) or short (S) cytoplasmic domain (2,3). KIR proteins are thought to play an important role in regulation of the immune response (3). KIR2DS2 downregulates the cytotoxicity of NK cells upon recognition of specific class I major histocompatibility complex (MHC) molecules on target cells and is a receptor on natural killer (NK) cells for HLA-C alleles (3,4).
    Molecular Weight
    Predicted: 28, 33, 37 kDa

    Observed: 34, 42 kDa
    Gene ID
    100132285
    NCBI Accession
    NP_036444
    UniProt
    P43631
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