SARS-CoV-2 ORF8 antibody (C-Term)
Reactivity: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, IHC
Host: Rabbit
Polyclonal
unconjugated
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- Target See all SARS-CoV-2 ORF8 products
- SARS-CoV-2 ORF8
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Binding Specificity
- C-Term
- Reactivity
- SARS Coronavirus-2 (SARS-CoV-2)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SARS-CoV-2 ORF8 antibody is un-conjugated
- Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Specificity
- ORF8 Antibody is predicted to not cross-react with other coronavirus family members.
- Purification
- SARS-CoV-2 (COVID-19) ORF8 Antibody is affinity chromatography purified via peptide column.
- Immunogen
- Anti-SARS-CoV-2 (COVID-19) ORF8 antibody was raised against a peptide corresponding to 14 amino acids near carboxyl terminus of SARS-CoV-2 (COVID-19) ORF8 protein. The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF8 protein.
- Isotype
- IgG
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- Application Notes
- WB: 1 μ,g/mL, IHC: 0.1 μ,g/mL Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) ORF8 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. It can detect SARS-CoV-2 ORF8 recombinant protein by ELISA and WB. All other applications and species not yet tested.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- SARS-CoV-2 (COVID-19) ORF8 antibody is supplied in PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,4 °C
- Storage Comment
- SARS-CoV-2 (COVID-19) ORF8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- SARS-CoV-2 ORF8
- Abstract
- SARS-CoV-2 ORF8 Products
- Target Type
- Viral Protein
- Background
- Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF8, ORF9b, ORF9c and ORF10. ORF8 may play a role in modulating host immune response (Probable). May play a role in blocking host IL17 cytokine by its interaction with host IL17RA (3).
- Molecular Weight
- 14kD kDa
- Gene ID
- 43740577
- UniProt
- P0DTC8
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