FGFR3 antibody (AA 166-375)

Catalog No. ABIN7434086

This Rabbit Polyclonal antibody specifically detects FGFR3 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for FGFR3 antibody (AA 166-375) (ABIN7434086)

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGFR3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FGFR3 Antibody

Binding Specificity: AA 166-375

Purpose: Polyclonal Antibody to Fibroblast Growth Factor Receptor 3 (FGFR3)

Specificity: The antibody is a rabbit polyclonal antibody raised against FGFR3. It has been selected for its ability to recognize FGFR3 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Fibroblast Growth Factor Receptor 3 (FGFR3) corresdonding to Val166~Gly375 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for FGFR3

Target: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Alternative Name: FGFR3

Background: CD333, ACH, CEK2, JTK4, Achondroplasia, Thanatophoric Dwarfism

UniProt: P22607

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding