FRS2 antibody (AA 239-449)

Catalog No. ABIN7439384

This Rabbit Polyclonal antibody specifically detects FRS2 in WB, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for FRS2 antibody (AA 239-449) (ABIN7439384)

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FRS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-FRS2 Antibody

Binding Specificity: AA 239-449

Purpose: Polyclonal Antibody to Fibroblast Growth Factor Receptor Substrate 2 (FRS2)

Specificity: The antibody is a rabbit polyclonal antibody raised against FRS2. It has been selected for its ability to recognize FRS2 in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Fibroblast Growth Factor Receptor Substrate 2 (FRS2) corresdonding to Asp239~Asn449 (Accession # Q8WU20)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,1:100-400Immunohistochemistry: 5-20 μg/mL,1:10-40Immunocytochemistry: 5-20 μg/mL,1:10-40Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.32 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for FRS2

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Alternative Name: FRS2

Background: SNT1, FRS2A, FRS2Alpha, SNT, SNT-1, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1

UniProt: Q8WU20

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2