CASR antibody (AA 863-1079)

Catalog No. ABIN7440848

This Rabbit Polyclonal antibody specifically detects CASR in WB, IHC, ICC and IP. It exhibits reactivity toward Mouse.

Quick Overview for CASR antibody (AA 863-1079) (ABIN7440848)

Target: CASR (Calcium-Sensing Receptor (CASR))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-CASR Antibody

Binding Specificity: AA 863-1079

Purpose: Polyclonal Antibody to Calcium Sensing Receptor (CASR)

Specificity: The antibody is a rabbit polyclonal antibody raised against CASR. It has been selected for its ability to recognize CASR in immunohistochemical staining and western blotting.

Cross-Reactivity: Human, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Calcium Sensing Receptor (CASR) corresdonding to Lys863~Ser1079 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.31 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for CASR

Target: CASR (Calcium-Sensing Receptor (CASR))

Alternative Name: CASR

Background: CAR, FHH, FIH, GPRC2A, HHC, HHC1, NSHPT, PCAR1, Parathyroid cell calcium-sensing receptor 1, Hypocalciuric Hypercalcemia 1, Severe Neonatal Hyperparathyroidism

UniProt: Q9QY96

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis