IRS1 antibody (AA 837-1089)

Catalog No. ABIN7440875

This Rabbit Polyclonal antibody specifically detects IRS1 in WB, IHC, ICC and IP. It exhibits reactivity toward Mouse.

Quick Overview for IRS1 antibody (AA 837-1089) (ABIN7440875)

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-IRS1 Antibody

Binding Specificity: AA 837-1089

Purpose: Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1)

Specificity: The antibody is a rabbit polyclonal antibody raised against IRS1. It has been selected for its ability to recognize IRS1 in immunohistochemical staining and western blotting.

Cross-Reactivity: Cow, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Insulin Receptor Substrate 1 (IRS1) corresdonding to Pro837~Gln1089 (Accession # P35569)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.2-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Alternative Name: IRS1

Background: HIRS1

UniProt: P35569

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process