PAR1 antibody (AA 46-109)

Catalog No. ABIN7440959

The Rabbit Polyclonal anti-PAR1 antibody is suitable to detect PAR1 in samples from Rat. It has been validated for IHC.

Quick Overview for PAR1 antibody (AA 46-109) (ABIN7440959)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PAR1 Antibody

Binding Specificity: AA 46-109

Purpose: Polyclonal Antibody to Protease Activated Receptor 1 (PAR1)

Specificity: The antibody is a rabbit polyclonal antibody raised against PAR1. It has been selected for its ability to recognize PAR1 in immunohistochemical staining and western blotting.

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Protease Activated Receptor 1 (PAR1) corresdonding to Ser46~Thr109 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 500 μg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: PAR1

Background: FIIR, F2r, CF2R, HTR, PAR1, TR, Coagulation Factor II Receptor, Thrombin Receptor

UniProt: P26824

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus