NR1H2 antibody (AA 1-446)

Catalog No. ABIN7444937

The Rabbit Polyclonal anti-NR1H2 antibody (ABIN7444937) specifically detects NR1H2 in WB, IHC, ICC and IP. The antibody is reactive with Mouse samples.

Quick Overview for NR1H2 antibody (AA 1-446) (ABIN7444937)

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1H2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-NR1H2 Antibody

Binding Specificity: AA 1-446

Purpose: Polyclonal Antibody to Liver X Receptor Beta (LXRb)

Specificity: The antibody is a rabbit polyclonal antibody raised against LXRb. It has been selected for its ability to recognize LXRb in immunohistochemical staining and western blotting.

Cross-Reactivity: Human, Pig, Rat

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Liver X Receptor Beta (LXRb) corresdonding to Met1~Glu446

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.01-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for NR1H2

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Alternative Name: LXRb

Background: NR1-H2, UNR, LXR-B, NER, NER-I, RIP15, Nuclear Receptor Subfamily 1,Group H,Member 2, Ubiquitously-Expressed Nuclear Receptor, Oxysterols receptor LXR-beta

UniProt: Q60644

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding