HMGCR antibody (AA 638-887)

Catalog No. ABIN7435559

Product Details anti-HMGCR Antibody

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Binding Specificity: AA 638-887

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purpose: Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR)

Specificity: The antibody is a rabbit polyclonal antibody raised against HMGCR. It has been selected for its ability to recognize HMGCR in immunohistochemical staining and western blotting.

Cross-Reactivity: Human, Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) corresdonding to Ala638~Ala887 with N-terminal His Tag

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-2 μg/mL

Immunohistochemistry: 5-20 μg/mL

Immunocytochemistry: 5-20 μg/mL

Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for HMGCR

Target: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Alternative Name: 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR Products)

Synonyms: HMGR antibody, LDLCQ3 antibody, hmg-coa-r antibody, HMG-CoAR antibody, Red antibody, 3H3M antibody, BcDNA:LD15354 antibody, CG10367 antibody, Clb antibody, DmHMG-CoAr antibody, Dmel\\CG10367 antibody, HMGCR antibody, HMGCR_Dm antibody, HMGCoAR antibody, HMGCoARr antibody, HMGCoAr antibody, HmG-CoAR antibody, Hmg antibody, bro1 antibody, bs32f05.y1 antibody, clb antibody, hmgc antibody, hmgcr antibody, hmgrc antibody, l(3)01152 antibody, l(3)04684 antibody, hmgcr2 antibody, im:6912716 antibody, zgc:110746 antibody, 3-hydroxy-3-methylglutaryl-CoA reductase antibody, 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog antibody, 3-hydroxy-3-methylglutaryl-Coenzyme A reductase antibody, HMG Coenzyme A reductase antibody, 3-hydroxy-3-methylglutaryl-CoA reductase b antibody, HMGCR antibody, hmgcr.L antibody, Hmgcr antibody, hmgcrb antibody

Background: HMG-CoA Reductase, Hydroxymethylglutaryl-CoA Reductase

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha