LYN antibody (AA 263-491)

Catalog No. ABIN7436321

This Rabbit Polyclonal antibody specifically detects LYN in WB, IHC, IP and ICC. It exhibits reactivity toward Human.

Quick Overview for LYN antibody (AA 263-491) (ABIN7436321)

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LYN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-LYN Antibody

Binding Specificity: AA 263-491

Purpose: Polyclonal Antibody to V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN)

Specificity: The antibody is a rabbit polyclonal antibody raised against LYN. It has been selected for its ability to recognize LYN in immunohistochemical staining and western blotting.

Cross-Reactivity: Mouse

Purification: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN) corresdonding to Val263~Pro491 (Accession # P07948)

Isotype: IgG

Application Details

Application Notes: Western blotting: 0.5-2 μg/mL,1:110-440,Immunohistochemistry: 5-20 μg/mL,1:11-44,Immunocytochemistry: 5-20 μg/mL,1:11-44,Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.22 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for LYN

Target: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Alternative Name: V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog

Background: JTK8, p53Lyn, p56Lyn, Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase

UniProt: P07948

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling