COX4NB antibody

Catalog No. ABIN7234922

Product Details anti-COX4NB Antibody

Target: COX4NB (COX4 Neighbor (COX4NB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX4NB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human EMC8

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX4NB

Target: COX4NB (COX4 Neighbor (COX4NB))

Alternative Name: EMC8 (COX4NB Products)

Synonyms: COX4NB antibody, NOC4 antibody, MGC75783 antibody, cox4nb antibody, fb54g02 antibody, noc4 antibody, wu:fb54g02 antibody, zgc:56331 antibody, C16orf2 antibody, C16orf4 antibody, FAM158B antibody, Cox4nb antibody, Fam158b antibody, Noc4 antibody, ER membrane protein complex subunit 8 antibody, ER membrane protein complex subunit 8 S homeolog antibody, ER membrane protein complex subunit 9 antibody, EMC8 antibody, emc8 antibody, emc8.S antibody, EMC9 antibody, Emc8 antibody

Background: COX4NB (Neighbor of COX4) is a 210 amino acid protein encoded by the human gene COX4NB. COX4NB belongs to the UPF0172 (NOC4) family and is found on chromosome 16, adjacent to the gene that encodes COX4. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16 through the CREBBP gene which encodes a critical CREB binding protein. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other auto-immune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.

Molecular Weight: 24 kDa

UniProt: O43402