FADD antibody
Quick Overview for FADD antibody (ABIN7235044)
Target
See all FADD AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human FADD
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Isotype
- IgG
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibody
FADD Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 20-150) antibodyFADD Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 5A6A2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD Reactivity: Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD Reactivity: Mouse WB, IHC Host: Rabbit Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reactivity: Human WB, IHC, ELISA, IF, ICC Host: Mouse Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reactivity: Human WB, PLA Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-80) antibodyFADD Reactivity: Human, Mouse, Rat, Monkey, Pig WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD Reactivity: Human WB, FACS Host: Rabbit Monoclonal 23GB3590 unconjugated Recombinant Antibody
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Application Notes
- WB 1:1000-1:5000, IHC 1:50-1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Alternative Name
- FADD
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Background
- The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
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Molecular Weight
- 23 kDa
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UniProt
- Q13158
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Pathways
- Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
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