PRMT7 antibody

Catalog No. ABIN7235467

This Rabbit Polyclonal antibody specifically detects PRMT7 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PRMT7 antibody (ABIN7235467)

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRMT7 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant protein of human PRMT7

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRMT7

Target: PRMT7 (Protein Arginine Methyltransferase 7 (PRMT7))

Alternative Name: PRMT7

Background: Protein arginine methyltransferase 7is aproteinthat in humans is encoded by thePRMT7gene.Argininemethylationis an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, usingS-adenosylmethionine(AdoMet) as the methyl donor. Arginine methylation is implicated insignal transduction, RNA transport, andRNA splicing. May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers. Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).

Molecular Weight: 78 kDa

UniProt: Q9NVM4

Pathways: Ribonucleoprotein Complex Subunit Organization